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Changes in Cellular mRNA Stability, Splicing and Polyadenylation through HuR Protein Sequestration by a Cytoplasmic RNA Virus

The impact of RNA viruses on the post-transcriptional regulation of cellular gene expression is unclear. Sindbis virus causes a dramatic relocalization of the cellular HuR protein from the nucleus to the cytoplasm in infected cells. This is due to the expression of large amounts of viral RNAs that c...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Barnhart, Michael D., Moon, Stephanie L., Emch, Alexander W., Wilusz, Carol J., Wilusz, Jeffrey
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849337/
https://ncbi.nlm.nih.gov/pubmed/24210824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.10.012
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