Fingolimod (FTY720) Stimulates Ca(2+)/Calcineurin Signaling in Fission Yeast

Fingolimod hydrochloride (FTY720) is the first in class of sphingosine 1-phosphate (S1P) receptor modulator approved to treat multiple sclerosis via down-regulation of G protein-coupled S1P receptor 1 by its phosphorylated form (FTY720-P). Many studies have revealed that FTY720 exerts various biolog...

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Autors principals: Hagihara, Kanako, Kita, Ayako, Mizukura, Aya, Yao, Mariko, Kitai, Yuki, Kunoh, Tatsuki, Masuko, Takashi, Matzno, Sumio, Chiba, Kenji, Sugiura, Reiko
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849299/
https://ncbi.nlm.nih.gov/pubmed/24312601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081907
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