A genome-wide screen for FTY720-sensitive mutants reveals genes required for ROS homeostasis

Fingolimod hydrochloride (FTY720), a sphingosine-1-phosphate (S1P) analogue, is an approved immune modulator for the treatment of multiple sclerosis (MS). Notably, in addition to its well-known mode of action as an S1P modulator, accumulating evidence suggests that FTY720 induces apoptosis in variou...

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Detaylı Bibliyografya
Yayımlandı:Microb Cell
Asıl Yazarlar: Hagihara, Kanako, Kinoshita, Kanako, Ishida, Kouki, Hojo, Shihomi, Kameoka, Yoshinori, Satoh, Ryosuke, Takasaki, Teruaki, Sugiura, Reiko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Shared Science Publishers OG 2017
Konular:
Microbiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722642/
https://ncbi.nlm.nih.gov/pubmed/29234668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2017.12.601
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