A genome-wide screen for FTY720-sensitive mutants reveals genes required for ROS homeostasis

Fingolimod hydrochloride (FTY720), a sphingosine-1-phosphate (S1P) analogue, is an approved immune modulator for the treatment of multiple sclerosis (MS). Notably, in addition to its well-known mode of action as an S1P modulator, accumulating evidence suggests that FTY720 induces apoptosis in variou...

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書目詳細資料
發表在:Microb Cell
Main Authors: Hagihara, Kanako, Kinoshita, Kanako, Ishida, Kouki, Hojo, Shihomi, Kameoka, Yoshinori, Satoh, Ryosuke, Takasaki, Teruaki, Sugiura, Reiko
格式: Artigo
語言:Inglês
出版: Shared Science Publishers OG 2017
主題:
Microbiology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722642/
https://ncbi.nlm.nih.gov/pubmed/29234668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2017.12.601
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