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A genome-wide screen for FTY720-sensitive mutants reveals genes required for ROS homeostasis
Fingolimod hydrochloride (FTY720), a sphingosine-1-phosphate (S1P) analogue, is an approved immune modulator for the treatment of multiple sclerosis (MS). Notably, in addition to its well-known mode of action as an S1P modulator, accumulating evidence suggests that FTY720 induces apoptosis in variou...
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| Yayımlandı: | Microb Cell |
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| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Shared Science Publishers OG
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5722642/ https://ncbi.nlm.nih.gov/pubmed/29234668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2017.12.601 |
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