Direct Reprogramming of Human Fibroblasts toward a Cardiomyocyte-like State

Direct reprogramming of adult somatic cells into alternative cell types has been shown for several lineages. We previously showed that GATA4, MEF2C, and TBX5 (GMT) directly reprogrammed nonmyocyte mouse heart cells into induced cardiomyocyte-like cells (iCMs) in vitro and in vivo. However, GMT alone...

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Hoofdauteurs: Fu, Ji-Dong, Stone, Nicole R., Liu, Lei, Spencer, C. Ian, Qian, Li, Hayashi, Yohei, Delgado-Olguin, Paul, Ding, Sheng, Bruneau, Benoit G., Srivastava, Deepak
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849259/
https://ncbi.nlm.nih.gov/pubmed/24319660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2013.07.005
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