Analysis of Induced Pluripotent Stem Cells from a BRCA1 Mutant Family

Understanding BRCA1 mutant cancers is hampered by difficulties in obtaining primary cells from patients. We therefore generated and characterized 24 induced pluripotent stem cell (iPSC) lines from fibroblasts of eight individuals from a BRCA1 5382insC mutant family. All BRCA1 5382insC heterozygous f...

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Detalhes bibliográficos
Main Authors: Soyombo, Abigail A., Wu, Yipin, Kolski, Lauren, Rios, Jonathan J., Rakheja, Dinesh, Chen, Alice, Kehler, James, Hampel, Heather, Coughran, Alanna, Ross, Theodora S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849250/
https://ncbi.nlm.nih.gov/pubmed/24319668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2013.08.004
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