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HIV-1 envelope glycoprotein signatures that correlate with the development of cross-reactive neutralizing activity

BACKGROUND: Current HIV-1 envelope glycoprotein (Env) vaccines are unable to induce cross-reactive neutralizing antibodies. However, such antibodies are elicited in 10-30% of HIV-1 infected individuals, but it is unknown why these antibodies are induced in some individuals and not in others. We hypo...

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Autors principals: van den Kerkhof, Tom L G M, Feenstra, K Anton, Euler, Zelda, van Gils, Marit J, Rijsdijk, Linda W E, Boeser-Nunnink, Brigitte D, Heringa, Jaap, Schuitemaker, Hanneke, Sanders, Rogier W
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849187/
https://ncbi.nlm.nih.gov/pubmed/24059682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-102
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