Longer V1V2 Region with Increased Number of Potential N-Linked Glycosylation Sites in the HIV-1 Envelope Glycoprotein Protects against HIV-Specific Neutralizing Antibodies

Human immunodeficiency virus type 1 (HIV-1) has the ability to adapt to the host environment by escaping from host immune responses. We previously observed that escape from humoral immunity, both at the individual and at a population level, coincided with longer variable loops and an increased numbe...

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Main Authors: van Gils, Marit J., Bunnik, Evelien M., Boeser-Nunnink, Brigitte D., Burger, Judith A., Terlouw-Klein, Marijke, Verwer, Naomi, Schuitemaker, Hanneke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126602/
https://ncbi.nlm.nih.gov/pubmed/21593147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00268-11
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