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NK4 Antagonizes Tbx1/10 to Promote Cardiac versus Pharyngeal Muscle Fate in the Ascidian Second Heart Field

The heart and head muscles share common developmental origins and genetic underpinnings in vertebrates, including humans. Parts of the heart and cranio-facial musculature derive from common mesodermal progenitors that express NKX2-5, ISL1, and TBX1. This ontogenetic kinship is dramatically reflected...

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Detalles Bibliográficos
Main Authors: Wang, Wei, Razy-Krajka, Florian, Siu, Eric, Ketcham, Alexandra, Christiaen, Lionel
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849182/
https://ncbi.nlm.nih.gov/pubmed/24311985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001725
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