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Activation of p38 MAPK is required in monocytic and neuronal cells for HIV gp120-induced neurotoxicity()

HIV-1 envelope protein gp120 has been implicated in neurotoxin production by monocytic cells, namely macrophages and microglia, and the pathogenesis of HIV-1 associated neurocognitive disorders (HAND). We previously showed in cerebrocortical cell cultures from rodents containing microglia, astrocyte...

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Bibliographic Details
Main Authors: Medders, Kathryn E., Sejbuk, Natalia, Maung, Ricky, Desai, Maya K., Kaul, Marcus
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848867/
https://ncbi.nlm.nih.gov/pubmed/20855878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902535
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