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PAF Makes It EZ(H2) for β-Catenin Transactivation
In this issue of Molecular Cell, Park and colleagues (Jung et al., 2013) show that PAF (PCNA-associated factor) binds to and hyperactivates transcriptional function of β-catenin in colon cancer cells by recruiting EZH2 to the coactivator complex. PAF-β-catenin and PAF-PCNA interactions are competiti...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3848709/ https://ncbi.nlm.nih.gov/pubmed/24210173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.10.008 |
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