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Proteomic analysis of mismatch repair-mediated alkylating agent-induced DNA damage response
BACKGROUND: Mediating DNA damage-induced apoptosis is an important genome-maintenance function of the mismatch repair (MMR) system. Defects in MMR not only cause carcinogenesis, but also render cancer cells highly resistant to chemotherapeutics, including alkylating agents. To understand the mechani...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3848634/ https://ncbi.nlm.nih.gov/pubmed/24330662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-3-37 |
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