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Rapid parallel flow cytometry assays of active GTPases using effector beads

We describe a rapid assay for measuring the cellular activity of small GTPases in response to a specific stimulus. Effector functionalized beads are used to quantify in parallel multiple, GTP-bound GTPases in the same cell lysate by flow cytometry. In a biologically relevant example, five different...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Buranda, Tione, BasuRay, Soumik, Swanson, Scarlett, Agola, Jacob, Bondu, Virginie, Wandinger-Ness, Angela
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848308/
https://ncbi.nlm.nih.gov/pubmed/23928044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2013.07.039
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