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Transient cytochalasin-D treatment induces apically administered rAAV2 across tight junctions for transduction of enterocytes
Enteropathogens are known to disrupt apical actin filaments and/or tight-junction barriers of intestinal epithelial cells to promote infection. In this study, we show that a controlled, cytochalasin-D (Cyto-D)-mediated disruption of actin filaments and tight junctions enhanced the apical delivery of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for General Microbiology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3848193/ https://ncbi.nlm.nih.gov/pubmed/19008386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.2008/001446-0 |
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