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P-Glycoprotein-Activity Measurements in Multidrug Resistant Cell Lines: Single-Cell versus Single-Well Population Fluorescence Methods

Background. P-gp expression has been linked to the efflux of chemotherapeutic drugs in human cancers leading to multidrug resistance. Fluorescence techniques have been widely applied to measure the P-gp activity. In this paper, there is a comparison between the advantages of two fluorescence approac...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pasquier, Jennifer, Rioult, Damien, Abu-Kaoud, Nadine, Marie, Sabine, Rafii, Arash, Guerrouahen, Bella S., Le Foll, Frank
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848087/
https://ncbi.nlm.nih.gov/pubmed/24350282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/676845
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