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Increased levels of anti-non-Gal IgG following pig-to-baboon bone marrow transplantation correlate with failure of engraftment

BACKGROUND: The development of genetically modified pigs which lack the expression of alpha 1–3 galactosyl transferase, (GalT-KO pigs) has facilitated the xenogeneic transplantation of porcine organs and tissues into primates by avoiding hyperacute rejection due to pre-existing antibodies against th...

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Detalhes bibliográficos
Main Authors: Liang, Fan, Wamala, Isaac, Scalea, Joseph, Tena, Aseda, Cormack, Taylor, Pratts, Shannon, Struuck, Raimon Duran, Elias, Nahel, Hertl, Martin, Huang, Christene A., Sachs, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848062/
https://ncbi.nlm.nih.gov/pubmed/24289469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12065
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