Occurrence of specific humoral non-responsiveness to swine antigens following administration of GalT-KO bone marrow to baboons

BACKGROUND: Hematopoietic chimerism induces transplantation tolerance across allogeneic and xenogeneic barriers, but has been difficult to achieve in the pig-to-primate model. We have now utilized swine with knockout of the gene coding for α-1,3-galactosyltransferase (GalT-KO pigs) as bone marrow do...

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Main Authors: Griesemer, Adam, Liang, Fan, Hirakata, Atsushi, Hirsh, Erica, Lo, Diana, Okumi, Masayoshi, Sykes, Megan, Yamada, Kazuhiko, Huang, Christene A., Sachs, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942069/
https://ncbi.nlm.nih.gov/pubmed/20723202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1399-3089.2010.00600.x
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