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Salmonella typhi encodes a functional cytolethal distending toxin that is delivered into host cells by a bacterial-internalization pathway

Many bacterial pathogens encode the cytolethal distending toxin (CDT), which causes host cells to arrest during their cell cycle by inflicting DNA damage. CDT is composed of three proteins, CdtA, CdtB, and CdtC. CdtB is the enzymatically active or A subunit, which possesses DNase I-like activity, wh...

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Bibliografische gegevens
Hoofdauteurs: Haghjoo, Erik, Galán, Jorge E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2004
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC384795/
https://ncbi.nlm.nih.gov/pubmed/15070766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400932101
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