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Yeast genome-wide drug-induced haploinsufficiency screen to determine drug mode of action

Methods to systematically test drugs against all possible proteins in a cell are needed to identify the targets underlying their therapeutic action and unwanted effects. Here, we show that a genome-wide drug-induced haploinsufficiency screen by using yeast can reveal drug mode of action in yeast and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Baetz, Kristin, McHardy, Lianne, Gable, Ken, Tarling, Tamsin, Rebérioux, Delphine, Bryan, Jenny, Andersen, Raymond J., Dunn, Teresa, Hieter, Phil, Roberge, Michel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC384780/
https://ncbi.nlm.nih.gov/pubmed/15070751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307122101
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