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H4K16 acetylation marks active genes and enhancers of embryonic stem cells, but does not alter chromatin compaction

Compared with histone H3, acetylation of H4 tails has not been well studied, especially in mammalian cells. Yet, H4K16 acetylation is of particular interest because of its ability to decompact nucleosomes in vitro and its involvement in dosage compensation in flies. Here we show that, surprisingly,...

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Autores principales: Taylor, Gillian C.A., Eskeland, Ragnhild, Hekimoglu-Balkan, Betül, Pradeepa, Madapura M., Bickmore, Wendy A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847775/
https://ncbi.nlm.nih.gov/pubmed/23990607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.155028.113
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