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An EM algorithm based on an internal list for estimating haplotype distributions of rare variants from pooled genotype data
BACKGROUND: Pooling is a cost effective way to collect data for genetic association studies, particularly for rare genetic variants. It is of interest to estimate the haplotype frequencies, which contain more information than single locus statistics. By viewing the pooled genotype data as incomplete...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3847674/ https://ncbi.nlm.nih.gov/pubmed/24034507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-14-82 |
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