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DC-SIGN gene promoter variants and IVIG treatment response in Kawasaki disease

BACKGROUND: Genetic variants in the inhibiting FcγRIIB mediate anti-inflammatory responses and influence IVIG refractoriness (IVIG-R). However, these variants are rare in Asian and Hispanic populations so other genes in the pathway could be potentially involved. IVIG is ineffective in mice lacking S...

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Detalhes bibliográficos
Main Authors: Portman, Michael A, Wiener, Howard W, Silva, Miriam, Shendre, Aditi, Shrestha, Sadeep
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847673/
https://ncbi.nlm.nih.gov/pubmed/24006904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1546-0096-11-32
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