Functional FcγRIIB Gene Variants Influence Intravenous Immunoglobulin (IVIG) Response in Kawasaki Disease (KD) Patients

In Kawasaki Disease patients, the authors show associations between high-dose intravenous immunoglobulin (IVIG) response and a polymorphism in the FCγRIIB. This provides basis for defining the IVIG regulatory mechanisms and pharmacogenomic approach to IVIG therapy.

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Detalhes bibliográficos
Main Authors: Shrestha, Sadeep, Wiener, Howard, Olson, Aaron K., Edberg, Jeffrey C, Bowles, Neil E., Patel, Hitendra, Portman, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444515/
https://ncbi.nlm.nih.gov/pubmed/21601260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.04.027
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