Evolving potassium channels by means of yeast selection reveals structural elements important for selectivity

Potassium channels are widely distributed. To serve their physiological functions, such as neuronal signaling, control of insulin release, and regulation of heart rate and blood flow, it is essential that K(+) channels allow K(+) but not the smaller and more abundant Na(+) ions to go through. The na...

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Main Authors: Bichet, Delphine, Lin, Yu-Fung, Ibarra, Christian A., Huang, Cindy Shen, Yi, B. Alexander, Jan, Yuh Nung, Jan, Lily Yeh
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2004
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC384766/
https://ncbi.nlm.nih.gov/pubmed/15070737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401195101
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