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Evolving potassium channels by means of yeast selection reveals structural elements important for selectivity

Potassium channels are widely distributed. To serve their physiological functions, such as neuronal signaling, control of insulin release, and regulation of heart rate and blood flow, it is essential that K(+) channels allow K(+) but not the smaller and more abundant Na(+) ions to go through. The na...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Bichet, Delphine, Lin, Yu-Fung, Ibarra, Christian A., Huang, Cindy Shen, Yi, B. Alexander, Jan, Yuh Nung, Jan, Lily Yeh
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2004
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384766/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15070737/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0401195101
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