Clinical Implications of Co-Inhibitory Molecule Expression in the Tumor Microenvironment for DC Vaccination: A Game of Stop and Go

The aim of therapeutic dendritic cell (DC) vaccines in cancer immunotherapy is to activate cytotoxic T cells to recognize and attack the tumor. T cell activation requires the interaction of the T cell receptor with a cognate major-histocompatibility complex-peptide complex. Although initiated by ant...

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Detalhes bibliográficos
Main Authors: Vasaturo, Angela, Di Blasio, Stefania, Peeters, Deborah G. A., de Koning, Coco C. H., de Vries, Jolanda M., Figdor, Carl G., Hato, Stanleyson V.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847559/
https://ncbi.nlm.nih.gov/pubmed/24348481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00417
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