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The arginine finger of bacteriophage T7 gene 4 helicase: Role in energy coupling
The DNA helicase encoded by gene 4 of bacteriophage T7 couples DNA unwinding to the hydrolysis of dTTP. The loss of coupling in the presence of orthovanadate (Vi) suggests that the γ-phosphate of dTTP plays an important role in this mechanism. The crystal structure of the hexameric helicase shows Ar...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC384754/ https://ncbi.nlm.nih.gov/pubmed/15070725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400968101 |
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