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Disruption of communication between peripheral and central trigeminovascular neurons mediates the antimigraine action of 5HT(1B/1D) receptor agonists

Triptans are 5HT(1B/1D) receptor agonists commonly prescribed for migraine headache. Although originally designed to constrict dilated intracranial blood vessels, the mechanism and site of action by which triptans abort the migraine pain remain unknown. We showed recently that sensitization of perip...

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Autori principali: Levy, Dan, Jakubowski, Moshe, Burstein, Rami
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC384731/
https://ncbi.nlm.nih.gov/pubmed/15016917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306147101
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