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Disruption of communication between peripheral and central trigeminovascular neurons mediates the antimigraine action of 5HT(1B/1D) receptor agonists

Triptans are 5HT(1B/1D) receptor agonists commonly prescribed for migraine headache. Although originally designed to constrict dilated intracranial blood vessels, the mechanism and site of action by which triptans abort the migraine pain remain unknown. We showed recently that sensitization of perip...

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Detalhes bibliográficos
Main Authors: Levy, Dan, Jakubowski, Moshe, Burstein, Rami
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC384731/
https://ncbi.nlm.nih.gov/pubmed/15016917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306147101
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