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The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cells
Ectopic activation of the Wnt signaling pathway is highly oncogenic for many human tissues. Here, we show that ectopic Wnt signaling increases the effective stem cell activity in mouse mammary glands in vivo. Furthermore, Wnt effectors induce the accumulation of mouse mammary epithelial progenitors...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC384711/ https://ncbi.nlm.nih.gov/pubmed/15020770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400699101 |
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