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The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cells

Ectopic activation of the Wnt signaling pathway is highly oncogenic for many human tissues. Here, we show that ectopic Wnt signaling increases the effective stem cell activity in mouse mammary glands in vivo. Furthermore, Wnt effectors induce the accumulation of mouse mammary epithelial progenitors...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Bob Y., McDermott, Sean P., Khwaja, Shariq S., Alexander, Caroline M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC384711/
https://ncbi.nlm.nih.gov/pubmed/15020770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400699101
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