FamClash: A method for ranking the activity of engineered enzymes

This article introduces the computational procedure FamClash for analyzing incompatibilities in engineered protein hybrids by using protein family sequence data. All pairs of residue positions in the sequence alignment that conserve the property triplet of charge, volume, and hydrophobicity are firs...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Saraf, Manish C., Horswill, Alexander R., Benkovic, Stephen J., Maranas, Costas D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2004
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384708/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14981242/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0400065101
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