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FamClash: A method for ranking the activity of engineered enzymes
This article introduces the computational procedure FamClash for analyzing incompatibilities in engineered protein hybrids by using protein family sequence data. All pairs of residue positions in the sequence alignment that conserve the property triplet of charge, volume, and hydrophobicity are firs...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14981242/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0400065101 |
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