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FamClash: A method for ranking the activity of engineered enzymes
This article introduces the computational procedure FamClash for analyzing incompatibilities in engineered protein hybrids by using protein family sequence data. All pairs of residue positions in the sequence alignment that conserve the property triplet of charge, volume, and hydrophobicity are firs...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC384708/ https://ncbi.nlm.nih.gov/pubmed/14981242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400065101 |
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