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Microspheres targeted with a mesothelin antibody and loaded with doxorubicin reduce tumor volume of human mesotheliomas in xenografts
BACKGROUND: Malignant mesotheliomas (MMs) are chemoresistant tumors related to exposure to asbestos fibers. The long latency period of MM (30-40 yrs) and heterogeneity of tumor presentation make MM difficult to diagnose and treat at early stages. Currently approved second-line treatments following s...
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Autori principali: | , , , , , , , , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
BioMed Central
2013
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3846908/ https://ncbi.nlm.nih.gov/pubmed/24024776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-400 |
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