Human papillomavirus (HPV) origin-binding protein associates with mitotic spindles to enable viral DNA partitioning

Human papillomaviruses (HPVs) establish long-term infections in patients. The mechanism for extrachromosomal HPV DNA persistence in cycling cells is unknown. We show that HPV origin-containing plasmids partition as minichromosomes, attributable to an association of the viral origin recognition prote...

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Detalhes bibliográficos
Main Authors: Van Tine, Brian A., Dao, Luan D., Wu, Shwu-Yuan, Sonbuchner, Timothy M., Lin, Biing Yuan, Zou, Nianxiang, Chiang, Cheng-Ming, Broker, Thomas R., Chow, Louise T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC384690/
https://ncbi.nlm.nih.gov/pubmed/15020762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306848101
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