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An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca(2+) entry
The STIM1-ORAI1 pathway of store-operated Ca(2+) entry is an essential component of cellular Ca(2+) signaling(1). STIM1 senses depletion of intracellular Ca(2+) stores in response to physiological stimuli, and relocalises within the endoplasmic reticulum (ER) to plasma membrane (PM)-apposed junction...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3846693/ https://ncbi.nlm.nih.gov/pubmed/23792561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12229 |
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