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An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca(2+) entry

The STIM1-ORAI1 pathway of store-operated Ca(2+) entry is an essential component of cellular Ca(2+) signaling(1). STIM1 senses depletion of intracellular Ca(2+) stores in response to physiological stimuli, and relocalises within the endoplasmic reticulum (ER) to plasma membrane (PM)-apposed junction...

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Главные авторы: Sharma, Sonia, Quintana, Ariel, Findlay, Gregory M, Mettlen, Marcel, Baust, Beate, Jain, Mohit, Nilsson, Roland, Rao, Anjana, Hogan, Patrick G
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846693/
https://ncbi.nlm.nih.gov/pubmed/23792561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12229
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