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ICOS Regulates the Generation and Function of Human CD4(+) Treg in a CTLA-4 Dependent Manner
Inducible co-stimulator (ICOS) is a member of CD28/Cytotoxic T-lymphocyte Antigen-4 (CTLA-4) family and broadly expressed in activated CD4(+) T cells and induced regulatory CD4(+) T cells (CD4(+) iTreg). ICOS-related signal pathway could be activated by the interaction between ICOS and its ligand (I...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3846688/ https://ncbi.nlm.nih.gov/pubmed/24312642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082203 |
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