ICOS Regulates the Generation and Function of Human CD4(+) Treg in a CTLA-4 Dependent Manner

Inducible co-stimulator (ICOS) is a member of CD28/Cytotoxic T-lymphocyte Antigen-4 (CTLA-4) family and broadly expressed in activated CD4(+) T cells and induced regulatory CD4(+) T cells (CD4(+) iTreg). ICOS-related signal pathway could be activated by the interaction between ICOS and its ligand (I...

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Bibliografiske detaljer
Main Authors: Zheng, Jian, Chan, Ping-Lung, Liu, Yinping, Qin, Gang, Xiang, Zheng, Lam, Kwok-Tai, Lewis, David B., Lau, Yu-Lung, Tu, Wenwei
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846688/
https://ncbi.nlm.nih.gov/pubmed/24312642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082203
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