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CD40-activated B cells are more potent than immature dendritic cells to induce and expand CD4(+) regulatory T cells
CD4(+) regulatory T cells (Tregs) play an important role in maintaining immune tolerance by suppressing pathologic immune responses. The generation of large numbers of antigen-specific Tregs ex vivo is critical for the development of clinical immunotherapy based on the adoptive transfer of Tregs. Bo...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4003254/ https://ncbi.nlm.nih.gov/pubmed/20081875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2009.103 |
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