Genotype-dependent Effects of TGFβ1 on Mast Cell Function: Targeting the Stat5 Pathway

We previously demonstrated that Transforming Growth Factor (TGF) β1 suppresses IgE-mediated signaling in human and mouse mast cells in vitro, an effect that correlated with decreased expression of the high affinity IgE receptor, FcεRI. The in vivo effects of TGFβ1 and the means by which it suppresse...

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Bibliographic Details
Main Authors: Fernando, Josephine, Faber, Travis W., Pullen, Nicholas A., Falanga, Yves T., Kolawole, Elizabeth Motunrayo, Oskeritzian, Carole A., Barnstein, Brian O., Bandara, Geethani, Li, Geqiang, Schwartz, Lawrence B., Spiegel, Sarah, Straus, David B., Conrad, Daniel H., Bunting, Kevin D., Ryan, John J.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846427/
https://ncbi.nlm.nih.gov/pubmed/24068671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202723
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