Mitochondrial DNA damage is associated with reduced mitochondrial bioenergetics in Huntington’s disease

Oxidative stress and mitochondrial dysfunction have been implicated in the pathology of HD, however the precise mechanisms by which mutant huntingtin modulates levels of oxidative damage in turn resulting in mitochondrial dysfunction are not known. We hypothesize that mutant huntingtin increases oxi...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Siddiqui, Almas, Rivera-Sánchez, Sulay, del R. Castro, María, Acevedo-Torres, Karina, Rane, Anand, Torres-Ramos, Carlos A., Nicholls, David G., Andersen, Julie K., Ayala-Torres, Sylvette
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846402/
https://ncbi.nlm.nih.gov/pubmed/22709585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.06.008
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares