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Mitochondrial DNA damage is associated with reduced mitochondrial bioenergetics in Huntington’s disease
Oxidative stress and mitochondrial dysfunction have been implicated in the pathology of HD, however the precise mechanisms by which mutant huntingtin modulates levels of oxidative damage in turn resulting in mitochondrial dysfunction are not known. We hypothesize that mutant huntingtin increases oxi...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
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2012
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| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3846402/ https://ncbi.nlm.nih.gov/pubmed/22709585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.06.008 |
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