CaMKII in cerebral ischemia

Ischemic insults on neurons trigger excessive, pathological glutamate release that causes Ca(2+) overload resulting in neuronal cell death (excitotoxicity). The Ca(2+)/calmodulin (CaM)-dependent protein kinase II (CaMKII) is a major mediator of physiological excitatory glutamate signals underlying n...

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Main Authors: Coultrap, Steven J, Vest, Rebekah S, Ashpole, Nicole M, Hudmon, Andy, Bayer, K Ulrich
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2011
主題:
Review
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846291/
https://ncbi.nlm.nih.gov/pubmed/21685929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.68
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