Efficient Generation of Human iPS Cells by a Synthetic Self-Replicative RNA

The generation of human induced Pluripotent Stem (iPS) cells holds great promise for development of regenerative medicine therapies to treat a wide range of human diseases. However, the generation of iPS cells in the absence of integrative DNA vectors remains problematic. Here we report a simple, hi...

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Détails bibliographiques
Auteurs principaux: Yoshioka, Naohisa, Gros, Edwige, Li, Hai-Ri, Kumar, Shantanu, Deacon, Dekker C., Maron, Cornelia, Muotri, Alysson R., Chi, Neil C., Fu, Xiang-Dong, Yu, Benjamin D., Dowdy, Steven F.
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845961/
https://ncbi.nlm.nih.gov/pubmed/23910086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.06.001
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