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Symmetry-constrained Analysis of Pulsed Double Electron-Electron Resonance (DEER) Spectroscopy Reveals the Dynamic Nature of the KcsA Activation Gate

Distance determination from an echo intensity modulation obtained by pulsed double electron-electron resonance (DEER) experiment is a mathematically ill-posed problem. Tikhonov regularization yields distance distributions that can be difficult to interpret, especially in system with multiple discret...

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Autors principals: Dalmas, Olivier, Hyde, H. Clark, Hulse, Raymond E., Perozo, Eduardo
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845908/
https://ncbi.nlm.nih.gov/pubmed/22946877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3069038
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