Tpl2 knockout keratinocytes have increased biomarkers for invasion and metastasis

Skin cancer is the most common form of cancer in the USA, with an estimated two million cases diagnosed annually. Tumor progression locus 2 (Tpl2), also known as MAP3K8, is a serine/threonine protein kinase in the mitogen-activated protein kinase signal transduction cascade. Tpl2 was identified by o...

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Hauptverfasser: DeCicco-Skinner, Kathleen L., Jung, Sarah A., Tabib, Tracy, Gwilliam, J.Curtis, Alexander, Hepzibha, Goodheart, Sarah E., Merchant, Anand S., Shan, Mengge, Garber, Caroline, Wiest, Jonathan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845897/
https://ncbi.nlm.nih.gov/pubmed/24067898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt319
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