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Loss of tumor progression locus 2 (tpl2) enhances tumorigenesis and inflammation in two-stage skin carcinogenesis

Tumor progression locus 2 (Tpl2) is a serine/threonine kinase in the mitogen-activated protein kinase signal transduction cascade known to regulate inflammatory pathways. Previously identified as an oncogene, its mutation or overexpression is reported in a variety of human cancers. To address its ro...

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Bibliografische gegevens
Hoofdauteurs: DeCicco-Skinner, KL, Trovato, EL, Simmons, JK, Lepage, PK, Wiest, JS
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460638/
https://ncbi.nlm.nih.gov/pubmed/20935675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.447
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