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Development of a Capillary Electrophoresis Platform for Identifying Inhibitors of Protein-Protein Interactions

Methods for identifying chemical inhibitors of protein-protein interactions (PPIs) are often prone to discovery of false positives, particularly those caused by molecules that induce protein aggregation. Thus, there is interest in developing new platforms that might allow earlier identification of t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rauch, Jennifer N., Nie, Jing, Buchholz, Tonia J., Gestwicki, Jason E., Kennedy, Robert T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845662/
https://ncbi.nlm.nih.gov/pubmed/24060167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac4023082
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