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In Astrocytes the Accumulation of the Immunity-Related GTPases Irga6 and Irgb6 at the Vacuole of Toxoplasma gondii Is Dependent on the Parasite Virulence

Toxoplasma gondii is an obligate intracellular protozoan parasite responsible for a common infection of the central nervous system. Interferon (IFN)γ is the key cytokine of host defence against T. gondii. However, T. gondii strains differ in virulence and T. gondii factors determining virulence are...

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Bibliografiske detaljer
Main Authors: Lubitz, Felix P., Degrandi, Daniel, Pfeffer, Klaus, Mausberg, Anne K.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845628/
https://ncbi.nlm.nih.gov/pubmed/24324375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/480231
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