Inhibition of CaMKK β and CaMK IV is detrimental in cerebral ischemia

BACKGROUND AND PURPOSE: Elevation of intracellular calcium was traditionally thought to be detrimental in stroke pathology. However, clinical trials testing treatments which block calcium signaling have failed to improve outcomes in ischemic stroke. Emerging data suggest that calcium may also trigge...

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Huvudupphovsmän: McCullough, Louise D., Tarabishy, Sami, Benashski, Sharon, Xu, Yan, Ribar, Thomas, Means, Anthony, Li, Jun
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845442/
https://ncbi.nlm.nih.gov/pubmed/23868268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.113.001030
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